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This was shown to inhibit steroidogenesis through a dominate-negative effect by altering the translocation of cholesterol from the mitochondria to the TAT-CRAC domain

PMID: 28051332

Without food: Some people prefer to take carnitine on an empty stomach, particularly before exercise

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These fatty acids are a dense, crucial source of potential energy, but they cannot cross into the mitochondrial matrixthe innermost compartment where energy production occurswithout a specialized transport mechanism