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2) Conduct extensive clinical trials to determine the efficacy and safety of stem cell- and nanotechnology-based therapies ( These efforts should be complemented by strong interdisciplinary collaborations that integrate insights from genetics, molecular biology, pharmacology, and clinical sciences to streamline the translation of research findings into effective DR therapies

Restless Legs Syndrome Is Associated with Mast Cell Activation Syndrome. Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine, vol

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doi: 10.1016/j.ijcard.2011.07.083 147

This fact is relevant as transgenic mice overexpressing IGFBP-2 were resistant to developing obesity when fed with high fat diet [174], suggesting that this molecule could have a direct effect on preadipocyte differentiation