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This finding indicates that ORM2 is not secreted by astrocytes themselves, but rather, it is more probable that ORM2 is secreted by hepatic hepatocytes and may enter the central nervous system via a compromised BBB (Roy et al., 2024)

In the model cytosolic GSH has three fates: it is transported into the blood, there is a net flux to GSSG, and 0.2% is removed per hour corresponding to detoxification reactions and excretion into the bile

The composite specimen was immersed for 2 h in 0.1 mM Gt in 0.5 M HCl solution, and UVvis spectra were retaken

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Velazquez et al., 2023)