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Description
ROS, which stem from aerobic metabolism, various stressors, or disruptions in antioxidant defenses, influence cellular fate by regulating their levels [6]

Pyrroloquinoline quinone induces cancer cell apoptosis via mitochondrial-dependent pathway and down-regulating cellular bcl-2 protein expression
A survival response of mammalian cells

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Acknowledgements We thank the Tsinghua University Branch of the China National Center for Protein Sciences (Beijing) for providing facility support

It inhibits NF-kB activation, reduces pro-inflammatory cytokine Adv Exp Med Biol VIP Vasoactive Intestinal Peptide for Immunomodulation VIP is a 28-amino acid neuropeptide with broad immunomodulatory effects
