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2012, Zhou et al., Ferrari et al

It is interesting that sex differences in the response to nestorone IN treatment were found, showing as improving functional outcomes and reducing ischemic lesions in male mice, but having no effect in female mice at 48 h postMCAO [210]

(2021) 28(11):192235.e5
Its claim to fame in the research community is its pleiotropic effectsmeaning it appears to influence multiple biological pathways simultaneously
