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Particularly, in some embodiments, the CpG-Ab immunoconjugate specifically binds to a tumor-associated antigen selected from CD19, CD20, CD22, CD25, CD30, CD33, CD38, CD40, CD44, CD45R (B220), CD49, CD52, CD56, CD70, CD74, CD79a, CD79b, CD93, CD123, CD138, CD163, CD205, CD206, CD274, CD303, and CD304, folate receptor alpha, folate receptor beta, mesothelin, PSMA, Her-2, EGFR, CLDN18.2, 5T4, CD47,nectin4, transferrin receptor, integrin, cripto, EphA2, AGS-5, AGS-16, CanAg, EpCAM, IL4 receptor, IL2 receptor, Lewis Y, GPNMB and Trop2

Chemotherapies work for some cancers but not others. In one study of 34 patients conducted by the University of Iowa and published in November 2024, researchers found that incorporating vitamin C into treatment plans nearly doubled life expectancy for patients with late-stage pancreatic cancer, extending median time of survival from 8.3 months to 16 months

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doi:10.1002/jor.21107 Bock-Marquette I, Saxena A, White MD, DiMaio JM, Srivastava D

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