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The European Food Safety Authority sets the NOAEL at 1g/kg/day
Tsang, D., Ho, K
Carcinogenesis 23, 13991404
Thiamine also appears to have direct anti-inflammatory effects in the gut of ruminant animals, showing a reduction in intestinal permeability through enhanced production of barrier proteins, protection against bacterial lipopolysaccharide-induced inflammation, and improved barrier function
The induction of autophagy was a result of Akt/mTOR/p7056K pathway inhibition and ERK pathway activation
Zella M
