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Astrocytes from ALS patients release inflammatory molecules instead of providing energy support, which is often responsible for microglia shifting to an inflammatory state incurring neuronal damage (Table 2)

It is also a potent antioxidant that neutralizes free radicals that cause chronic diseases

The difference map and distance curves indicated that genomic contacts at distances of approximately 75 to 800 kb were reduced in the cnd1-K658E mutant compared to wild-type cells (Fig

Frei B: Reactive oxygen species and antioxidant vitamins: Mechanism of action

Analyses of circulating tumor DNA (ctDNA) indicated that reduced baseline mutant allele fractions might correlate with improved clinical outcomes [343]
