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Preclinical results demonstrating the ability of ficlatuzumab to mitigate the effects of tumor-associated fibroblasts on proliferation, migration, and invasion were recently published (36)
[DOI] [PMC free article] [PubMed] [Google Scholar] Johnson LR
10.1016/j.bmcl.2011.05.022 [DOI] [PubMed] [Google Scholar] 103.Becherer JD, Boros EE, Carpenter TY, Cowan DJ, Deaton DN, Haffner CD, et al
Toxins 13 (9), 603
The inter-assay variability range has now been added into the text (Results, line 4): This assay has an inter-assay coefficient of variability of 8.8 % as calculated with a single serum sample measured on 18 different plates (24.11 2.12 ng/ml (SD)
PINEALON is one of a handful of synthetic peptides called peptide bioregulators for its ability to interact directly with DNA to alter gene expression
