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Lack of gastritis and of an adaptive immune response in interferon regulatory factor-1-deficient mice infected with Helicobacter pylori

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analyzed approximately 17,000 single cells from human OA cartilage and identified a ferroptosis-prone chondrocyte cluster (C1-3-4) with distinct expression of ferroptosis-related genes

Impaired adrenal catecholamine system function in mice with deficiency of the ascorbic acid transporter (SVCT2) FASEB J

The closest structural relative was found to be human CLIC1 (PDB code 1K0O), in which 156 C could be aligned with a root-mean-square deviation (RMSD) value of 0.93 , followed by GSTO1 from Homo sapiens (PDB code 3LFL) (122 aligned C with an RMSD of 2.07 ) and the putative stringent starvation protein A from Burkholderia cenocepacia (PDB code 4QQ7) (122 aligned C with an RMSD of 2.14 ) 12,15

The results showed that xCT inhibitor reduced the expression level of MUC1-C by inhibiting MUC1-C/xCT pathway, induced ferroptosis and finally inhibited the survival rate of TNBC cells [372]