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Moreover, through the modification of tissue targeting groups and microenvironment responsive groups, nanomedicine can respond to the high ROS levels at the oxidative damage site for precise drug delivery, enhancing the therapeutic effect and reducing the side effects [201, 202]
Instead, the FDA removed enforcement priority for these compounds, effectively treating them as neither affirmed nor prohibited in the bulk substance framework

[DOI] [PMC free article] [PubMed] [Google Scholar] 108.Randles D, Kam JWY, Heine SJ, Inzlicht M, Handy TC

Xie Y, Zhu S, Song X, Sun X, Fan Y, Liu J, et al