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Like POLG mutations, other genetic abnormalities that impair mtDNA replication, including C10orf2 , DGUOK , MPV17 , PEO1 , and SUCLG1 , are part of the hepatocerebral mitochondrial DNA depletion syndromes, which are syndromes that include prominent liver failure (70, 75, 76)

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The anti-inflammatory effects involve inflammatory mediator and signaling pathway suppression

Identification of p53 as a sequence-specific DNA-binding protein

Mingrone, G., et al.: L-carnitine improves glucose disposal in type 2 diabetic patients