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While one should avoid high doses of B vitamins, because high doses of certain vitamins can produce unwanted side effects, especially those that are fat-soluble, which the body holds in reserve

In comparing the structures of selenomethionine or methionine, you can see that the only difference is that selenium has been substituted for the sulfur (S) atom in methionine

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Lipid peroxides as potential causes of cataracts, lead to the changes of not only the lens cell membrane, but also of the cytosol, because it serves to reduce concentration of glutathione and cause the change of redox relationship GSH/GSSG 1