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Phosphorylation and positive regulation of the phosphorylation process are usually involved in cell growth, apoptosis and signaling pathways through post-translational modification and cellular metabolism, and abnormal alteration in phosphorylation contribute to diseases, including cancers 29

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2014;147(1):96-108.e4

The first example is citrate-derived acetyl-CoA, whose production is increased by PI3K/AKT-mediated ATP-citrate lyase (ACLY) enzyme [29]

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