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TNF- antagonists or TNFR knockdown suppress c-Jun N-terminal kinase (JNK) phosphorylation and alleviate BTZ-induced mechanical hypersensitivity (Zhang et al., 2014)

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Curcumin prevents alcohol-induced liver disease in rats by inhibiting the expression of NF-kappa B-dependent genes

It also functions as a signalling metabolite as the substrate for lysine acetylation reactions, enabling the modulation of protein functions in response to acetyl-CoA availability

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