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Age-related cohesion loss around centromeres, a significant contributor to errors in chromosome segregation, is exacerbated by ROS-induced oxidation and carbonylation of proteins essential for spindle formation and stability, thereby increasing the risk of aneuploidy in offspring [4, 38]

Type 1 Diabetes Mellitus Canine diabetes, like human diabetes, is divided into two types: type 1 diabetes and type 2 diabetes, with the former being insulin-dependent and the latter being non-insulin-dependent [155]

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