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Footnotes Peer review under responsibility of King Saud University

However, studies addressing the therapeutic use of supplemental L-carnitine in dialysis patients are few and have characteristically included small numbers of patients

Since there are known APOE -dependent differences in the gut microbiota in both humans and APOE-TR mice (Tran et al., 2019), L-carnitine metabolism could be impacted and, in turn, affect cerebrovascular function by disturbing normal L-carnitine shuttle function, particularly if other vulnerabilities are present

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PMID: 35012788 7 Trimethylaminuria

Numerous studies emphasize the significant dependency of AML cells on glutamine metabolism