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Comparison of ER/PR and HER2 statuses in primary and paired liver metastatic sites of breast carcinoma in patients with or without treatment

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In pre-clinical models of allergic asthma and allergic conjunctivitis, rEV131 has been shown to bind histamine very tightly and block mast-cell degranulation, reducing itching and inflammation associated with histamine release in the allergic response 31 ( Chapin M et al

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Researchers must also generate non-clinical evidence demonstrating that the compound interacts with the intended target and produces the expected pharmacological effects without showing major safety concerns

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