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In line with the potential of ABC transporters to efflux anticancer agents, their overexpression has been associated with poor response to chemotherapy and multidrug resistance (MDR) 27

Identification of the gene responsible for methylmalonic aciduria and homocystinuria, cblC type

Interestingly, inhibition of ferroptosis can usually be detected once upon sorafenib resistance occurs

doi: 10.1016/S0021-9258(19)38410-8

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Despite the recent identification of several constituents of the ROS signaling system, understanding how ROS-derived signals are incorporated to ultimately control biological processes like plant growth, development, stress adaptability as well as programmed cell death remains a challenge