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We processed each tilted data set individually using cryoSPARC 40 and focused on enriching for rare particle orientations by iteratively training Topaz 39 to pick non-preferred orientation particles for each tilt set

Longo J, Hamilton RJ, Masoomian M, Khurram N, Branchard E, Mullen PJ

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Extracorporeal shock wave therapy for Peyronies disease: exploratory meta-analysis of clinical trials