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While brown adipose tissue (BAT) traditionally relies on UCP1-mediated proton leak for non-shivering thermogenesis (NST), this process incurs substantial reactive oxygen species (ROS) production

The system Xc, a dimer consisting of SLC7A11 and SLC3A2, exchanges glutamate (Glu) out of the cell and cystine into the cell at a ratio of 1:1 [27, 28]

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Glutathione has the unique ability to donate an electron to Vitamin C, "recharging" it so it can go back to work