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Serum IgE levels were significantly reduced, and the mRNA and protein levels of eotaxin, migration inhibitory factor (MIF), IL-4, IL-5, and L-histidine decarboxylase were significantly reduced in ASX-treated mice

doi: 10.1007/s00125-008-0936-9 4 Baumel-AlterzonSKatzLSBrillGGarcia-OcanaAScottDK

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doi: 10.1139/y2012-090

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So, there is a systematic redistribution between the types of PUFAs present from highly unsaturated fatty acids to the less unsaturated that is region-specific