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doi: 10.1371/journal.pone.0087400 49 LiuJZhangZYangYDiTWuYBianT

Limitations and future directions Despite encouraging findings, further standardization is needed regarding PRP preparation, platelet concentration, and application protocols

Acknowledgements This work was supported by United States Public Health Service Grants DA00266 (to SHS) and a Research Scientist Award DA00074 (to SHS)

Mechanistically, valproate may cause somnolence by inhibiting the reuptake of GABA (and thereby potentiating GABA signaling in the brain)

10.2527/jas.2008-1698 198

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