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is supported by the Case Research Institute and the University Hospitals Case Medical Center

At low levels, exercise-induced ROS play a critical role in skeletal muscle adaptation [95] by up-regulating various cytokines and protein kinases such as tumor necrosis factor alpha (TNF-) [96] and mitogen-activated protein kinases (MAPK) [97] that work to signal increases in mitochondrial density and number, endogenous antioxidants, and assist in muscle protein synthesis [98, 99]

The Effect of Ergothioneine Supplementation on Cognitive Function, Memory, and Sleep in Older Adults with Subjective Memory Complaints: A Randomized Placebo-Controlled Trial

Prolonged exposure can contribute to respiratory problems, cognitive issues, digestive disturbances, and even mood disorders

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