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Animal models and clinical studies of ASD suggest that abnormalities in GABAergic neurons, signaling pathways, and related genes may play an important role in the pathogenesis of ASD, leading to abnormal levels of GABA in the blood and brain tissue of individuals with ASD

It is "metabolically expensive." It burns through energy faster than the average brain because it is hyper-sensitive to sensory input (light, sound, smell, barometric pressure)

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To examine transcriptional changes in vivo, we injected MG3 cells in mice that were then treated with the four conditions (control diet + DMSO local delivery, CMD diet + DMSO local delivery, control diet + RSL3 local delivery and CMD diet + RSL3 local delivery), and harvested the tumors after 3 days of treatment

doi: 10.3168/jds.2014-8220 143 ZhouZ.Vailati-RiboniM.TrevisiE.DrackleyJ

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