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Cancer 18 , 452 (2018)

The GLS2 gene is located on chromosome 12q13.3 and is composed of 19 exons that undergo alternative splicing to yield four mRNAs

It requires both glycine and glutamate to bind to it simultaneously for activation.[ref] Glutamate binds to the NMDA receptor, allowing calcium ions to flow into the neuron

Abouelmagd, S

*Correspondence: Ana Maria Castejon [email protected] This article was submitted to Child and Adolescent Psychiatry, a section of the journal Frontiers in Psychiatry Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Sulforaphane, a bioactive isothiocyanate generated from its precursor, glucoraphanin, in broccoli, brussels sprouts, and other cruciferous vegetables, is another well-characterized hormetin