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This is why the STEP trial protocol includes two intermediate doses (1.7 mg) before reaching 2.4 mg, and why many people find their sweet spot below maximum

Acknowledgments We thank the UK Biobank study, and the summary statistics data of UKB can be download from Neale lab ( and other GWAS summary-level data, which have been downloaded from We also thank all the reviewers and editors for their useful suggestions for improving this study

doi: 10.1021/tx0256127

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A: Shingrix works by strengthening the immune system's defenses against reactivation of the virus
