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1f ), another monocarbonyl analogue of curcumin, for its selective cytotoxicity activity against MCF-7 breast cancer cells (IC 50 = 5.6 M)

The high throughput screening campaign of the substance library provided several hit compounds one of those the drug-like aryl sulfonamide 40 that was subsequently optimized into 41 that is a metabolically stable and reversible IRAP inhibitor

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Nerve Health: Folate helps form myelin, which protects nerves, and supports the creation of neurotransmitters, which allow nerve cells to communicate

Cisplatin-induced hair cell death requires STAT1 and is attenuated by epigallocatechin gallate