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To counteract amyloid fibril formation that occurs with human Amy, a pair of helix-stabilizing mutations (N14E and V17R) were incorporated into Cagri 2

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In this review, we have tried to answer two questions: What changes occur in white matter in the course of AD and what is the relationship between these changes and the pathological hallmarks of the disease

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Patients should be told this directly, and it should appear in the consent conversation