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Joshua TG, Ayub A, Wijesinghe P, Nunez DA

PD-1+ and TIGIT+ Tregs migrate to sites of inflammation in a chemokine receptor-dependent manner, with CCR6 and CCR7 playing pivotal roles in their tissue homing

These molecules build up over time through a process called oxidation, and they can speed up cell aging and cause pre-mature cell damage

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