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Description
NNMT consumes S-adenosylmethionine (SAM) and methylates nicotinamide, depleting cellular methyl pools and downstream NAD+ precursors

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D. C. Morris, M. Chopp, L. Zhang, and Z. G. Zhang, Thymosin 4: a candidate for treatment of stroke?, Wiley, May 2010. doi: 10.1111/j.1749-6632.2010.05469.x

Some patients receiving Vitamin B12 injections report feeling worse after their treatment, an unexpected reaction considering these injections are typically used to alleviate symptoms of B12 deficiency

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