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Challenges and opportunities in drug and biomarker development for nonalcoholic steatohepatitis: findings and recommendations from an American Association for the study of Liver Diseases-U.S

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[3] Because sodium bicarbonate supplies a hypertonic sodium load, it expands extracellular volume and raises plasma osmolality

[DOI] [PubMed] [Google Scholar] 40.Malaguarnera M., Gargante M.P., Russo C., Antic T., Vacante M., Avitabile T., Li Volti G., Galvano F

Collectively, our findings reinforce that OCTN2 functions as a highly selective, high affinity transporter, mediating carnitine uptake via a Na + -dependent mechanism that, to our knowledge, has not been observed in the SLC22 family or in MFS transporters more broadly
