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Metabolomics and cancer: identification of biomarkers from plant-based pharmaceuticals using an integrated approach

MAPK14, one of the four p38 isoforms, and its upstream signalling pathways are identified to be required in mammalian cells for both starvation- and hypoxia-induced mitophagy, but not macroautophagy, demonstrating the selectivity of this pathway 124

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Considering that aqueous humor drainage occurs not only through intercellular pathways but also via transcellular routes, the permeability of the TM emerges as a primary factor in regulating IOP [414,415]