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Artesunate inhibits TGF-1-induced epithelial-to-mesenchymal differentiation (EMT) and RLE-6TN cell proliferation by upregulating Smad7 mRNA and protein expressions and downregulating Smad3, ACTA2, and Vim mRNA expressions (Wang et al., 2014)
You'll likely see it paired with methylparaben to cover the full range (including gram-negative bacteria)
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The initial inflammatory phase of wound healing, typically lasting 23 days in physiological wounds, is extended in chronic wounds 73
