glutathione redox cycle and peroxide The catalytic of SeCys. H2O2, hydrogen peroxide; GSH, The glutathione redox cycle, demonstrating

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During the last three decades, 4-hydroxy-2-nonenal (HNE), a major ,-unsaturated aldehyde product of n-6 fatty acid oxidation, has been shown to be involved in a great number of pathologies such as metabolic diseases, neurodegenerative diseases and cancers

Consistently, GPX3 deficiency generated opposite changes in both cell lines