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Studies show that only 1-5% of oral B12 actually reaches your bloodstream, particularly in individuals with absorption issues

Mitochondria play another crucial protective role in the decomposition of PUFAs, in which the mitochondrial enzyme 2,4-dienoyl-CoA reductase 1 (DECR1) predominantly mediates this process by reducing PUFAs to exert an anti-ferroptotic effect [169]

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[DOI] [PMC free article] [PubMed] [Google Scholar] 116.Han X, Tai H, Wang X, Wang Z, Zhou J, Wei X, Ding Y, Gong H, Mo C, Zhang J, Qin J, Ma Y, Huang N, et al

& Vargas, M