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Western blot analysis further confirmed that dedifferentiated melanocytes exhibited increased expression of cytoskeletal regulators (RhoA, Rac1/2/3, Cdc42, F-actin), Hippo effectors (YAP, WW domain-containing transcription regulator protein 1 [TAZ], CCN1, CCN2), MAPK signaling components (p-ERK, p-JNK), and AP-1 transcription factors, with c-Jun showing the strongest induction (5.6-fold increase) (Supplementary Fig

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