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Tirzepatide also activates the GIP receptor, opening a second hormonal pathway that enhances insulin secretion and energy expenditure

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At 8 weeks of age, both experimental groups displayed similar microbial diversity and did not exhibit any significant grouping based on their microbiome

SER-109 has completed phase II (NCT02437487), phase III (NCT03183128) and open-label phase III (NCT03183141) trials (McGovern et al., 2021