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Collectively, lung injury following I/R involves the interplay of gut-lung axis dysfunction, activation of inflammatory signaling, oxidative stress, and multiple cell death pathways

6 Discussion While the literature is full of evidence regarding the role of micronutrients in cancer prevention and the importance of managing deficiencies in oncologic patients, a major challenge is posed by the quality and heterogeneity of the available data

The entry of pro-inflammatory cytokines and neurotoxic compounds into the CNS triggers an inflammatory cascade linked to reactive oxygen species (ROS) production