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Approximately one fifth of sulfide exists as hydrosulfide ion (HS ) and the remaining four fifth consist mostly of H 2 S with little amount of S 2 in physiological fluids (37 C, pH 7.4) according to the Henderson-Hasselbalch equation [24]

Chem Biol 2005, 12 (4), 445452

1 Even though ADs pathogenesis is not completely clear, the aggregation of misfolded tau proteins that lead to the formation of intraneuronal neurofibrillary tangles, extracellular senile plaques, neuronal loss, and activation of microglia have been considered the main hallmarks of the disease

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2b left, Supplementary Fig