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Sitoindosides VIIX and withaferin A (glycowithanolides), the active components of WS, have been demonstrated to reactivate the main enzymes that scavenge free radicals in vivo [205]

doi: 10.1016/j.jprot.2013.11.014

Many individuals may notice improvements in overall skin radiance within 48 weeks, while more visible improvements in skin brightness and even-looking skin tone may take 812 weeks or longer of regular use

Immunol Rev (2010) 235:23443.10.1111/j.0105-2896.2010.00898.x 44 KaechSMAhmedR

X-box binding protein 1 (XBP1) transcriptionally regulates protein folding genes, while the unfolded protein response (UPR) activates when protein folding demands increase, reducing protein synthesis while expanding folding capacity (77)

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