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408 Studies have shown that the loss of GLP-1R in astrocytes can impair mitochondrial integrity, leading to the dysfunction and inhibition of glucose uptake and -oxidation

Global RAS activation induces the secretion of TNF- by macrophages, T cells, renal cells of the epithelium and mesangium, and cardiac cells (126128)

2020;88:102806 [cited 2020 mar 12] Available from: Ridpath JR, Nakamura J

Due to activation of the mTOR pathway, which regulates cell growth [18], and modulation of the ATF6 pathway, affecting cytoskeletal structure [19], senescent cells often take on an enlarged and irregular morphology [18, 19]

Compared with a low-Se diet (0.05 mg/kg), a high-Se diet (1.5 mg/kg) maintained postischemic plasma GSH levels and GPX activity and improved myocardial infarct size and postischemic mean arterial blood pressure in rats [115]

10.1161/ATVBAHA.120.314515 Arterioscler Thromb Vasc Biol