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10.1172/JCI31581 194 WangJ

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Oncology research 10(1112), 595603 (1997)

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[1] All identified published trials report mild or no side-effects of GSH use

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Administration of reduced glutathione in FOLFOX4 adjuvant treatment for colorectal cancer: Effect on oxaliplatin pharmacokinetics, Pt-DNA adduct formation, and neurotoxicity

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Additional replicates are needed to more robustly assess if this metabolite difference is statistically significant

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Oxidative glutamate toxicity involves mitochondrial dysfunction and perturbation of intracellular Ca2+ homeostasis

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