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PLOS ONE 9:e94530

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Mechanistic perspective of mitochondrial fusion: tubulation vs

Restoring NAD + levels with dietary precursors and targeting NAD + degradation enzymes with small-molecule inhibitors has emerged as a potential therapeutic strategy to restore NAD + levels, thereby providing opportunities for alleviating age-related decline and diseases (FIG

We describe the use of glutathione (GSH) for this purpose, which is present at elevated levels (10 mM) in various cancer cells [7]

Thorson JS Structure-Based Engineering of E
