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Indeed, RSL3 and erastin effectively abrogated clonogenic survival of adherent murine SCLC lines, which could be fully restored with Fer-1 co-treatment in the case of RSL3 and partially rescued in the case of erastin, which is known to also affect other pathways (Fig

[DOI] [PMC free article] [PubMed] [Google Scholar] 143.Klotz L

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Post-synthetic elaborations like polymer grafting or ligand conjugation need also to be standardized in order to reach equivalent levels of functionalization, which in turn affect pharmacokinetic properties and therapeutic activity

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