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doi: 10.3389/fmicb.2022.979719 Received 27 June 2022 Accepted 14 September 2022 Published 06 October 2022 Volume 13 - 2022 Edited by Wanbo Tai, Shenzhen Bay Laboratory, China Reviewed by Lihui Guo, University of Amsterdam, Netherlands

GHK-Cu is a copper-binding peptide discussed in the context of wound healing, tissue repair, and skin remodeling

Elevated ROS levels are a key finding in many diseases [234] including cardiovascular and neurodegenerative diseases, cancer, diabetes mellitus, and aging [88, 89, 197, 235237]

Moreover, the expression of FLAP mRNA displayed a significantly higher expression in non-stimulated (2,3-fold), in histamine (5,3-fold), in IL-4 (2,5-fold) and in IL-13 (10,7-fold) stimulated mast cells from AD patients as compared to cells from HVs (Fig

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