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Elam M et al

When Se deficiency occurs in the context of already existing hypothyroidism, the symptoms of myxedema (such as puffiness of the skin, a hoarse voice, and slowness of mental function) may become more pronounced [73]

doi: 10.1016/j.celrep.2019.05.105 494 WuSJiangZYSunYFYuBChenJDaiCQet al

As indicated in the text and figure legends, four to six biological replicates from mutants and controls at two ages (3 months and 8 months, male mice) were used for this experiment

Diets rich in omega-3 fatty acids, antioxidants, and polyphenolssuch as fatty fish, berries, dark leafy greens, walnuts, and olive oilmay support neuronal health and reduce oxidative stress within the brain

The activity of other selenoproteins, such as the thioredoxin reductases, were not examined in this report