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Clinical trials examining GHK-Cu effects on facial hyperpigmentation have reported variable results, with some studies documenting 15-30% reductions in melanin index measurements over 8-12 week treatment periods, while others report minimal pigment-lightening effects

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doi: 10.7196/SAMJ.2020.v110i3.14403

Results: Inhibits cell pigmentation

Under pathological conditions, microgliaas a function of different stimuliare activated to exert neuroprotective effects (M2 phenotype) or to release inflammatory factors and neurotoxic substances (M1 phenotype)