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Ethics statement The protocol of animal experiments was approved by the Ethics Committee of Zhejiang Baiyue Biotech Co., Ltd., for Experimental Animals Welfare (approval number: ZJBYLA-IACUC-20220901) and carried out under the guidelines of the National Institutes of Health on Animal Care and Use

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In addition to these effects, the supplemented synbiotics improved microbial colonization in the gut

In these patients, the excess of dietary methionine might even reduce their hyperhomocysteinemia by favoring homocysteine catabolism (Loehrer et al, 1996)

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