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[DOI] [PubMed] [Google Scholar] 38.Nagamatsu K., Inoue K., Terao T., Toki S

Increased methylglyoxal and oxidative stress in hypertensive rat vascular smooth muscle cells

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Furthermore, HRMS-based non-targeted analyses using MS/MS structural elucidation allowed to identify other relatively minor metabolites related to APAP-Cys such as S-(5-acetylamino-2-hydroxyphenyl)mercaptopyruvic acid (SAMP), an APAP metabolite potentially formed by the transamination reaction of APAP-cysteine (see Fig.1), previously observed in mouse ( 29 )
